Intracranial and spinal ependymoma: series at Faculdade de Medicina, Universidade de São Paulo

OBJECTIVE: Ependymomas are rare intracranial neuroepithelial tumors and the most common location is intramedullary. The aim was to analyze the characteristics of these tumors to determine the patients' overall survival and the likelihood of recurrence. METHOD: Data of clinical presentation, tumor location, duration of symptoms, degree of resection and complementary treatment of 34 patients with intracranial ependymoma and 31 with intramedullary ependymoma who underwent surgery in the last ten years were collected and correlated with the recurrence time and overall survival. RESULTS: There was statistically significant correlation between the degree of resection and intracranial tumor location, although it is not a hallmark of recurrence. Data analyses of intramedullary ependymoma did not show correlation with overall survival and likelihood of recurrence. CONCLUSION: The location of the intracranial tumor is connected with the degree of resection; however it is not a predictive factor to overall survival.

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Detalles Bibliográficos
Autores principales: Andrade,Fernanda Gonçalves de, Aguiar,Paulo Henrique Pires de, Matushita,Hamilton, Taricco,Mario Augusto, Oba-Shinjo,Sueli Mieko, Marie,Suely Kazue Nagahashi, Teixeira,Manoel Jacobsen
Formato: Digital revista
Idioma:English
Publicado: Academia Brasileira de Neurologia - ABNEURO 2009
Acceso en línea:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2009000400010
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Descripción
Sumario:OBJECTIVE: Ependymomas are rare intracranial neuroepithelial tumors and the most common location is intramedullary. The aim was to analyze the characteristics of these tumors to determine the patients' overall survival and the likelihood of recurrence. METHOD: Data of clinical presentation, tumor location, duration of symptoms, degree of resection and complementary treatment of 34 patients with intracranial ependymoma and 31 with intramedullary ependymoma who underwent surgery in the last ten years were collected and correlated with the recurrence time and overall survival. RESULTS: There was statistically significant correlation between the degree of resection and intracranial tumor location, although it is not a hallmark of recurrence. Data analyses of intramedullary ependymoma did not show correlation with overall survival and likelihood of recurrence. CONCLUSION: The location of the intracranial tumor is connected with the degree of resection; however it is not a predictive factor to overall survival.