Acute bacterial meningitis caused by Streptococcus pneumoniae resistant to the antimicrobian agents and their serotypes
The main objectives of this study are to evaluate the resistance rates of Streptococcus pneumonia to penicillin G, ceftriaxone and vancomycin in patients with meningitis; to analyze possible risk factors to the antimicrobian resistance; to describe the serotypes detected and to suggest an initial empirical treatment for meningitis. The sensitiveness and serotypes of all isolated S. pneumoniae of patients with acute bacterial meningitis received by the Paraná State Central Laboratory from April 2001 to august 2002 have been evaluated. One hundred S. pneumoniae have been isolated, of which 15% were resistant to penicillin, 1% to cephalosporin and 0% to vancomycin. The serotypes most found were 14 (19%), 3 and 23F (10% each). When only the resistant serotypes were analyzed, the most prevalent was the 14 with 44%. The risk factors found in relation to the S. pneumoniae resistance were: age under one year old (p=0.01) and previous use of antibiotic (p=0.046). The resistance rates found, which were moderate to penicillin, low to cephalosporin and neutral to vancomycin, suggest the isolated use of a 3rd generation cephalosporin as an initial empirical therapy for the treatment of acute bacterial meningitis with a communitarian background.
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Academia Brasileira de Neurologia - ABNEURO
2008
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oai:scielo:S0004-282X20080004000142008-09-10Acute bacterial meningitis caused by Streptococcus pneumoniae resistant to the antimicrobian agents and their serotypesRossoni,Andrea Maciel de OliveiraDalla Costa,Libera MariaBerto,Denize BonatoFarah,Sônia SantosGelain,MarileneBrandileone,Maria Cristina de CuntoRamos,Vitor Hugo MarianoAlmeida,Sergio Monteiro de Streptococcus pneumoniae pneumococcus meningitis antimicrobial resistance cerebrospinal fluid The main objectives of this study are to evaluate the resistance rates of Streptococcus pneumonia to penicillin G, ceftriaxone and vancomycin in patients with meningitis; to analyze possible risk factors to the antimicrobian resistance; to describe the serotypes detected and to suggest an initial empirical treatment for meningitis. The sensitiveness and serotypes of all isolated S. pneumoniae of patients with acute bacterial meningitis received by the Paraná State Central Laboratory from April 2001 to august 2002 have been evaluated. One hundred S. pneumoniae have been isolated, of which 15% were resistant to penicillin, 1% to cephalosporin and 0% to vancomycin. The serotypes most found were 14 (19%), 3 and 23F (10% each). When only the resistant serotypes were analyzed, the most prevalent was the 14 with 44%. The risk factors found in relation to the S. pneumoniae resistance were: age under one year old (p=0.01) and previous use of antibiotic (p=0.046). The resistance rates found, which were moderate to penicillin, low to cephalosporin and neutral to vancomycin, suggest the isolated use of a 3rd generation cephalosporin as an initial empirical therapy for the treatment of acute bacterial meningitis with a communitarian background.info:eu-repo/semantics/openAccessAcademia Brasileira de Neurologia - ABNEUROArquivos de Neuro-Psiquiatria v.66 n.3a 20082008-09-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2008000400014en10.1590/S0004-282X2008000400014 |
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Rossoni,Andrea Maciel de Oliveira Dalla Costa,Libera Maria Berto,Denize Bonato Farah,Sônia Santos Gelain,Marilene Brandileone,Maria Cristina de Cunto Ramos,Vitor Hugo Mariano Almeida,Sergio Monteiro de |
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Rossoni,Andrea Maciel de Oliveira Dalla Costa,Libera Maria Berto,Denize Bonato Farah,Sônia Santos Gelain,Marilene Brandileone,Maria Cristina de Cunto Ramos,Vitor Hugo Mariano Almeida,Sergio Monteiro de Acute bacterial meningitis caused by Streptococcus pneumoniae resistant to the antimicrobian agents and their serotypes |
author_facet |
Rossoni,Andrea Maciel de Oliveira Dalla Costa,Libera Maria Berto,Denize Bonato Farah,Sônia Santos Gelain,Marilene Brandileone,Maria Cristina de Cunto Ramos,Vitor Hugo Mariano Almeida,Sergio Monteiro de |
author_sort |
Rossoni,Andrea Maciel de Oliveira |
title |
Acute bacterial meningitis caused by Streptococcus pneumoniae resistant to the antimicrobian agents and their serotypes |
title_short |
Acute bacterial meningitis caused by Streptococcus pneumoniae resistant to the antimicrobian agents and their serotypes |
title_full |
Acute bacterial meningitis caused by Streptococcus pneumoniae resistant to the antimicrobian agents and their serotypes |
title_fullStr |
Acute bacterial meningitis caused by Streptococcus pneumoniae resistant to the antimicrobian agents and their serotypes |
title_full_unstemmed |
Acute bacterial meningitis caused by Streptococcus pneumoniae resistant to the antimicrobian agents and their serotypes |
title_sort |
acute bacterial meningitis caused by streptococcus pneumoniae resistant to the antimicrobian agents and their serotypes |
description |
The main objectives of this study are to evaluate the resistance rates of Streptococcus pneumonia to penicillin G, ceftriaxone and vancomycin in patients with meningitis; to analyze possible risk factors to the antimicrobian resistance; to describe the serotypes detected and to suggest an initial empirical treatment for meningitis. The sensitiveness and serotypes of all isolated S. pneumoniae of patients with acute bacterial meningitis received by the Paraná State Central Laboratory from April 2001 to august 2002 have been evaluated. One hundred S. pneumoniae have been isolated, of which 15% were resistant to penicillin, 1% to cephalosporin and 0% to vancomycin. The serotypes most found were 14 (19%), 3 and 23F (10% each). When only the resistant serotypes were analyzed, the most prevalent was the 14 with 44%. The risk factors found in relation to the S. pneumoniae resistance were: age under one year old (p=0.01) and previous use of antibiotic (p=0.046). The resistance rates found, which were moderate to penicillin, low to cephalosporin and neutral to vancomycin, suggest the isolated use of a 3rd generation cephalosporin as an initial empirical therapy for the treatment of acute bacterial meningitis with a communitarian background. |
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Academia Brasileira de Neurologia - ABNEURO |
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2008 |
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http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2008000400014 |
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