Event-related potentials (P300) and neuropsychological assessment in boys exhibiting Duchenne muscular dystrophy
OBJECTIVE: To examine auditory cognitive evoked potentials (P300 potentials) and neuropsychological dysfunction in patients with Duchenne muscular dystrophy (DMD). METHOD: P300 potentials and neuropsychological test results were obtained from 16 healthy control boys and 20 DMD patients. Full Intelligence Quotients (IQ) were estimated for patients and control group. Mean age was 9.5 years in the DMD patient group, and 10 years in the control group (p>0.05). RESULTS: The mean IQ values were 64.35 in the DMD patients and 82.68 in the control group (p=0.01). Mean P300 values were 347.6 in the DMD group and 337.4 in the control group (p=0.14). There was no significant correlation between parameters in each group. CONCLUSION: DMD patients showed a poor performance as evaluated by P300 potential compared to the control group, although the difference was not statistically significant. Systematic alterations in neuropsychological test results were found, the differences paralleling those detected in IQ.
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Academia Brasileira de Neurologia - ABNEURO
2007
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oai:scielo:S0004-282X20070001000132007-03-22Event-related potentials (P300) and neuropsychological assessment in boys exhibiting Duchenne muscular dystrophyDella Coletta,Marcus ViniciusScola,Rosana HerminiaWiemes,Gislaine Richter MinhotoFonseca,Cláudia NasserMäder,Maria JoanaFreund,Aline AndradeWerneck,Lineu César P300 Duchenne muscular dystrophy neuropsychologic dysfunction OBJECTIVE: To examine auditory cognitive evoked potentials (P300 potentials) and neuropsychological dysfunction in patients with Duchenne muscular dystrophy (DMD). METHOD: P300 potentials and neuropsychological test results were obtained from 16 healthy control boys and 20 DMD patients. Full Intelligence Quotients (IQ) were estimated for patients and control group. Mean age was 9.5 years in the DMD patient group, and 10 years in the control group (p>0.05). RESULTS: The mean IQ values were 64.35 in the DMD patients and 82.68 in the control group (p=0.01). Mean P300 values were 347.6 in the DMD group and 337.4 in the control group (p=0.14). There was no significant correlation between parameters in each group. CONCLUSION: DMD patients showed a poor performance as evaluated by P300 potential compared to the control group, although the difference was not statistically significant. Systematic alterations in neuropsychological test results were found, the differences paralleling those detected in IQ.info:eu-repo/semantics/openAccessAcademia Brasileira de Neurologia - ABNEUROArquivos de Neuro-Psiquiatria v.65 n.1 20072007-03-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2007000100013en10.1590/S0004-282X2007000100013 |
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Della Coletta,Marcus Vinicius Scola,Rosana Herminia Wiemes,Gislaine Richter Minhoto Fonseca,Cláudia Nasser Mäder,Maria Joana Freund,Aline Andrade Werneck,Lineu César |
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Della Coletta,Marcus Vinicius Scola,Rosana Herminia Wiemes,Gislaine Richter Minhoto Fonseca,Cláudia Nasser Mäder,Maria Joana Freund,Aline Andrade Werneck,Lineu César Event-related potentials (P300) and neuropsychological assessment in boys exhibiting Duchenne muscular dystrophy |
author_facet |
Della Coletta,Marcus Vinicius Scola,Rosana Herminia Wiemes,Gislaine Richter Minhoto Fonseca,Cláudia Nasser Mäder,Maria Joana Freund,Aline Andrade Werneck,Lineu César |
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Della Coletta,Marcus Vinicius |
title |
Event-related potentials (P300) and neuropsychological assessment in boys exhibiting Duchenne muscular dystrophy |
title_short |
Event-related potentials (P300) and neuropsychological assessment in boys exhibiting Duchenne muscular dystrophy |
title_full |
Event-related potentials (P300) and neuropsychological assessment in boys exhibiting Duchenne muscular dystrophy |
title_fullStr |
Event-related potentials (P300) and neuropsychological assessment in boys exhibiting Duchenne muscular dystrophy |
title_full_unstemmed |
Event-related potentials (P300) and neuropsychological assessment in boys exhibiting Duchenne muscular dystrophy |
title_sort |
event-related potentials (p300) and neuropsychological assessment in boys exhibiting duchenne muscular dystrophy |
description |
OBJECTIVE: To examine auditory cognitive evoked potentials (P300 potentials) and neuropsychological dysfunction in patients with Duchenne muscular dystrophy (DMD). METHOD: P300 potentials and neuropsychological test results were obtained from 16 healthy control boys and 20 DMD patients. Full Intelligence Quotients (IQ) were estimated for patients and control group. Mean age was 9.5 years in the DMD patient group, and 10 years in the control group (p>0.05). RESULTS: The mean IQ values were 64.35 in the DMD patients and 82.68 in the control group (p=0.01). Mean P300 values were 347.6 in the DMD group and 337.4 in the control group (p=0.14). There was no significant correlation between parameters in each group. CONCLUSION: DMD patients showed a poor performance as evaluated by P300 potential compared to the control group, although the difference was not statistically significant. Systematic alterations in neuropsychological test results were found, the differences paralleling those detected in IQ. |
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Academia Brasileira de Neurologia - ABNEURO |
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2007 |
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http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2007000100013 |
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