Magnetic resonance imaging in the evaluation of patients with aseptic meningoencephalitis and connective tissue disorders

OBJECTIVE: To describe the role of magnetic resonance imaging (MRI) in the evaluation of patients with chronic and recurrent aseptic meningitis.METHOD: A retrospective study of five patients with aseptic meningoencefalitis diagnosed by clinical and CSF findings. CT scans showed without no relevant findings. RESULTS: MRI showed small multifocal lesions hyperintense on T2 weighted images and FLAIR, with mild or no gadolinium enhancement, mainly in periventricular and subcortical regions. Meningoencephalitis preceded the diagnosis of the underlying disease in four patients (Behçet´s disease or systemic lupus erythematosus). After the introduction of adequate treatment for the rheumatic disease, they did not present further symptoms of aseptic meningoencephalitis. CONCLUSION: Aseptic meningoencephalitis can be an early presentation of an autoimmune disease. It is important to emphasize the role of MRI in the diagnosis and follow-up of these patients.

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Main Authors: APPENZELLER,SIMONE, KOBAYASHI,ELIANE, COSTALLAT,LILIAN T.L., ZANARDI,VERÔNICA DE ARAUJO, RIBEIRO NETO,JOSÉ MENEZES, DAMASCENO,BENITO PEREIRA, CENDES,FERNANDO
Format: Digital revista
Language:English
Published: Academia Brasileira de Neurologia - ABNEURO 2000
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2000000100007
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spelling oai:scielo:S0004-282X20000001000072000-04-03Magnetic resonance imaging in the evaluation of patients with aseptic meningoencephalitis and connective tissue disordersAPPENZELLER,SIMONEKOBAYASHI,ELIANECOSTALLAT,LILIAN T.L.ZANARDI,VERÔNICA DE ARAUJORIBEIRO NETO,JOSÉ MENEZESDAMASCENO,BENITO PEREIRACENDES,FERNANDO magnetic resonance imaging CNS vasculitis aseptic meningitis systemic lupus erythematosus lupus Behçet disease OBJECTIVE: To describe the role of magnetic resonance imaging (MRI) in the evaluation of patients with chronic and recurrent aseptic meningitis.METHOD: A retrospective study of five patients with aseptic meningoencefalitis diagnosed by clinical and CSF findings. CT scans showed without no relevant findings. RESULTS: MRI showed small multifocal lesions hyperintense on T2 weighted images and FLAIR, with mild or no gadolinium enhancement, mainly in periventricular and subcortical regions. Meningoencephalitis preceded the diagnosis of the underlying disease in four patients (Behçet´s disease or systemic lupus erythematosus). After the introduction of adequate treatment for the rheumatic disease, they did not present further symptoms of aseptic meningoencephalitis. CONCLUSION: Aseptic meningoencephalitis can be an early presentation of an autoimmune disease. It is important to emphasize the role of MRI in the diagnosis and follow-up of these patients.info:eu-repo/semantics/openAccessAcademia Brasileira de Neurologia - ABNEUROArquivos de Neuro-Psiquiatria v.58 n.1 20002000-03-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2000000100007en10.1590/S0004-282X2000000100007
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libraryname SciELO
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author APPENZELLER,SIMONE
KOBAYASHI,ELIANE
COSTALLAT,LILIAN T.L.
ZANARDI,VERÔNICA DE ARAUJO
RIBEIRO NETO,JOSÉ MENEZES
DAMASCENO,BENITO PEREIRA
CENDES,FERNANDO
spellingShingle APPENZELLER,SIMONE
KOBAYASHI,ELIANE
COSTALLAT,LILIAN T.L.
ZANARDI,VERÔNICA DE ARAUJO
RIBEIRO NETO,JOSÉ MENEZES
DAMASCENO,BENITO PEREIRA
CENDES,FERNANDO
Magnetic resonance imaging in the evaluation of patients with aseptic meningoencephalitis and connective tissue disorders
author_facet APPENZELLER,SIMONE
KOBAYASHI,ELIANE
COSTALLAT,LILIAN T.L.
ZANARDI,VERÔNICA DE ARAUJO
RIBEIRO NETO,JOSÉ MENEZES
DAMASCENO,BENITO PEREIRA
CENDES,FERNANDO
author_sort APPENZELLER,SIMONE
title Magnetic resonance imaging in the evaluation of patients with aseptic meningoencephalitis and connective tissue disorders
title_short Magnetic resonance imaging in the evaluation of patients with aseptic meningoencephalitis and connective tissue disorders
title_full Magnetic resonance imaging in the evaluation of patients with aseptic meningoencephalitis and connective tissue disorders
title_fullStr Magnetic resonance imaging in the evaluation of patients with aseptic meningoencephalitis and connective tissue disorders
title_full_unstemmed Magnetic resonance imaging in the evaluation of patients with aseptic meningoencephalitis and connective tissue disorders
title_sort magnetic resonance imaging in the evaluation of patients with aseptic meningoencephalitis and connective tissue disorders
description OBJECTIVE: To describe the role of magnetic resonance imaging (MRI) in the evaluation of patients with chronic and recurrent aseptic meningitis.METHOD: A retrospective study of five patients with aseptic meningoencefalitis diagnosed by clinical and CSF findings. CT scans showed without no relevant findings. RESULTS: MRI showed small multifocal lesions hyperintense on T2 weighted images and FLAIR, with mild or no gadolinium enhancement, mainly in periventricular and subcortical regions. Meningoencephalitis preceded the diagnosis of the underlying disease in four patients (Behçet´s disease or systemic lupus erythematosus). After the introduction of adequate treatment for the rheumatic disease, they did not present further symptoms of aseptic meningoencephalitis. CONCLUSION: Aseptic meningoencephalitis can be an early presentation of an autoimmune disease. It is important to emphasize the role of MRI in the diagnosis and follow-up of these patients.
publisher Academia Brasileira de Neurologia - ABNEURO
publishDate 2000
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2000000100007
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