Muscle biopsy correlated with electromyography: study of 100 cases

To find what the correlation is and verify if is possible to avoid extensive electromyographic examination, studying only one muscle, 100 patients with neuromuscular disorders (58 primary myopathies, 32 neurogenic disorders and 10 myotonic dystrophies) were submited to quantified electromyography (EMG) and muscle biopsy (MB) with fresh-frozen section plus histochemistry in the same muscle, but on the opposite side. The EMG was abnormal in 98% and MB in 93% of the cases. EMG and MB had a concordance of 84.3% in the neurogenic disorders and 84.77% in the primary myopathies. A correlation of 80% was obtained between all MB and EMG (including the cases of myotonic dystrophies), regarding the origin of the pathogenic process (p<0.01). The EMG had 5% inconsistences and the MB 11%, with respect to the pathogenic process. When the myotonic dystrophy was separated from the primary myopathies and from the denervation disorders, a complete concordance was found in all MB and had only 3.4% inconsistences in the denervation disorders and 3.1% in the primary myopathies.

Bibliographic Details

Main Authors:	Werneck,Lineu Cesar, Lima,José Geraldo Camargo
Format:	Digital revista
Language:	English
Published:	Academia Brasileira de Neurologia - ABNEURO 1988
Online Access:	http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1988000200006
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