Antiviral agents against equid alphaherpesviruses : current status and perspectives
Equid herpesvirus infections cause respiratory, neurological and reproductive syndromes. Despite preventive and control measures and the availability of vaccines and immunostimulants, herpesvirus infections still constitute a major threat to equine health and for the equine industry worldwide. Antiviral drugs, particularly nucleoside analogues and foscarnet, are successfully used for the treatment of human alphaherpesvirus infections. In equine medicine, the use of antiviral medications in alphaherpesvirus infections would decrease the excretion of virus and diminish the risk of contagion and the convalescent time in affected horses, and would also improve the clinical outcome of equine herpesvirus myeloencephalopathy. The combined use of antiviral compounds, along with vaccines, immune modulators, and effective preventive and control measures, might be beneficial in diminishing the negative impact of alphaherpesvirus infections in horses. The purpose of this review is to analyse the available information regarding the use of antiviral agents against alphaherpesviruses, with particular emphasis on equine alphaherpesvirus infections.
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Formato: | info:ar-repo/semantics/artículo biblioteca |
Idioma: | eng |
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2016
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Assuntos: | Enfermedades de los Animales, Viricidas, Alphavirus, Herpesviridae, Animal Diseases, Antiviral Agents, Herpesvirus, Alphaherpesvirus, |
Acesso em linha: | http://hdl.handle.net/20.500.12123/1220 http://www.sciencedirect.com/science/article/pii/S1090023315002543 https://doi.org/10.1016/j.tvjl.2015.06.010 |
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oai:localhost:20.500.12123-12202023-04-12T14:54:13Z Antiviral agents against equid alphaherpesviruses : current status and perspectives Thiry, Etienne Dal Pozzo, Fabiana Barrandeguy, Maria Edith Vissani, Maria Aldana Enfermedades de los Animales Viricidas Alphavirus Herpesviridae Animal Diseases Antiviral Agents Herpesvirus Alphaherpesvirus Equid herpesvirus infections cause respiratory, neurological and reproductive syndromes. Despite preventive and control measures and the availability of vaccines and immunostimulants, herpesvirus infections still constitute a major threat to equine health and for the equine industry worldwide. Antiviral drugs, particularly nucleoside analogues and foscarnet, are successfully used for the treatment of human alphaherpesvirus infections. In equine medicine, the use of antiviral medications in alphaherpesvirus infections would decrease the excretion of virus and diminish the risk of contagion and the convalescent time in affected horses, and would also improve the clinical outcome of equine herpesvirus myeloencephalopathy. The combined use of antiviral compounds, along with vaccines, immune modulators, and effective preventive and control measures, might be beneficial in diminishing the negative impact of alphaherpesvirus infections in horses. The purpose of this review is to analyse the available information regarding the use of antiviral agents against alphaherpesviruses, with particular emphasis on equine alphaherpesvirus infections. Inst.de Virología Fil: Vissani, Aldana. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología; Argentina Fil: Thiry, Etienne. University of Liege. Faculty of Veterinary Medicine. Veterinary Virology and Animal Viral Diseases and UREAR. Department of Infectious and Parasitic Diseases; Bélgica Fil: Dal Pozzo, Fabiana. University of Liege. Faculty of Veterinary Medicine. Veterinary Virology and Animal Viral Diseases and UREAR. Department of Infectious and Parasitic Diseases; Bélgica Fil: Barrandeguy, Maria Edith. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología; Argentina. Universidad del Salvador. Carrera de Veterinaria; Argentina 2017-09-14T14:20:56Z 2017-09-14T14:20:56Z 2016 info:ar-repo/semantics/artículo info:eu-repo/semantics/article info:eu-repo/semantics/acceptedVersion http://hdl.handle.net/20.500.12123/1220 http://www.sciencedirect.com/science/article/pii/S1090023315002543 1090-0233 https://doi.org/10.1016/j.tvjl.2015.06.010 eng info:eu-repo/semantics/restrictedAccess application/pdf Veterinary journal 207 : 38-44. (January 2016) |
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topic |
Enfermedades de los Animales Viricidas Alphavirus Herpesviridae Animal Diseases Antiviral Agents Herpesvirus Alphaherpesvirus Enfermedades de los Animales Viricidas Alphavirus Herpesviridae Animal Diseases Antiviral Agents Herpesvirus Alphaherpesvirus |
spellingShingle |
Enfermedades de los Animales Viricidas Alphavirus Herpesviridae Animal Diseases Antiviral Agents Herpesvirus Alphaherpesvirus Enfermedades de los Animales Viricidas Alphavirus Herpesviridae Animal Diseases Antiviral Agents Herpesvirus Alphaherpesvirus Thiry, Etienne Dal Pozzo, Fabiana Barrandeguy, Maria Edith Vissani, Maria Aldana Antiviral agents against equid alphaherpesviruses : current status and perspectives |
description |
Equid herpesvirus infections cause respiratory, neurological and reproductive syndromes. Despite preventive and control measures and the availability of vaccines and immunostimulants, herpesvirus infections still constitute a major threat to equine health and for the equine industry worldwide. Antiviral drugs,
particularly nucleoside analogues and foscarnet, are successfully used for the treatment of human alphaherpesvirus infections. In equine medicine, the use of antiviral medications in alphaherpesvirus infections would decrease the excretion of virus and diminish the risk of contagion and the convalescent
time in affected horses, and would also improve the clinical outcome of equine herpesvirus myeloencephalopathy. The combined use of antiviral compounds, along with vaccines, immune modulators, and effective preventive and control measures, might be beneficial in diminishing the negative impact of alphaherpesvirus infections in horses. The purpose of this review is to analyse the available information regarding the use of antiviral agents against alphaherpesviruses, with particular emphasis on equine alphaherpesvirus infections. |
format |
info:ar-repo/semantics/artículo |
topic_facet |
Enfermedades de los Animales Viricidas Alphavirus Herpesviridae Animal Diseases Antiviral Agents Herpesvirus Alphaherpesvirus |
author |
Thiry, Etienne Dal Pozzo, Fabiana Barrandeguy, Maria Edith Vissani, Maria Aldana |
author_facet |
Thiry, Etienne Dal Pozzo, Fabiana Barrandeguy, Maria Edith Vissani, Maria Aldana |
author_sort |
Thiry, Etienne |
title |
Antiviral agents against equid alphaherpesviruses : current status and perspectives |
title_short |
Antiviral agents against equid alphaherpesviruses : current status and perspectives |
title_full |
Antiviral agents against equid alphaherpesviruses : current status and perspectives |
title_fullStr |
Antiviral agents against equid alphaherpesviruses : current status and perspectives |
title_full_unstemmed |
Antiviral agents against equid alphaherpesviruses : current status and perspectives |
title_sort |
antiviral agents against equid alphaherpesviruses : current status and perspectives |
publishDate |
2016 |
url |
http://hdl.handle.net/20.500.12123/1220 http://www.sciencedirect.com/science/article/pii/S1090023315002543 https://doi.org/10.1016/j.tvjl.2015.06.010 |
work_keys_str_mv |
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_version_ |
1763176992777175040 |