Antiviral and antioxidant properties of active alginate edible films containing phenolic extracts

In this work, novel active edible films having antiviral activity were developed through the solvent casting method. Emulsified edible films were prepared by adding lipids into alginate films in order to improve their water vapour permeability. In addition, two natural extracts rich in phenolic compounds, specifically a green tea extract (GTE) and a grape seed extract (GSE) were used as active agents. Interestingly, incorporating GTE or GSE within the biopolymer matrix, the films exhibited significant antiviral activity against murine norovirus (MNV) and hepatitis A virus (HAV) since ∼2 log reduction were recorded for the 0.75 g extract/g alginate in the film, being GTE more efficient than GSE. Furthermore, the incorporation of phenolic compounds imparted antioxidant capacity to the active films, showing 14.79 ± 0.25 and 3.50 ± 0.25 mM Trolox⋅ g extract in the film−1 for 0.75 GTE and 0.75 GSE films, respectively. It was also found that water barrier efficiency improved upon addition of the highest amount of GTE or GSE (1:0.75 alginate:extract ratio) which was ascribed to molecular interactions between the films' components, as demonstrated by infrared spectroscopy assays.

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Bibliographic Details
Main Authors: Fabra, María José, Falcó, Irene, Randazzo, Walter, Sánchez Moragas, Gloria, López-Rubio, Amparo
Format: artículo biblioteca
Language:English
Published: Elsevier 2018-02-23
Subjects:Enteric viruses, Active packaging, Edible films, Grape seed extract (GSE), Green tee extract (GTE),
Online Access:http://hdl.handle.net/10261/162633
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spelling dig-iata-es-10261-1626332022-12-20T16:50:52Z Antiviral and antioxidant properties of active alginate edible films containing phenolic extracts Fabra, María José Falcó, Irene Randazzo, Walter Sánchez Moragas, Gloria López-Rubio, Amparo Enteric viruses Active packaging Edible films Grape seed extract (GSE) Green tee extract (GTE) In this work, novel active edible films having antiviral activity were developed through the solvent casting method. Emulsified edible films were prepared by adding lipids into alginate films in order to improve their water vapour permeability. In addition, two natural extracts rich in phenolic compounds, specifically a green tea extract (GTE) and a grape seed extract (GSE) were used as active agents. Interestingly, incorporating GTE or GSE within the biopolymer matrix, the films exhibited significant antiviral activity against murine norovirus (MNV) and hepatitis A virus (HAV) since ∼2 log reduction were recorded for the 0.75 g extract/g alginate in the film, being GTE more efficient than GSE. Furthermore, the incorporation of phenolic compounds imparted antioxidant capacity to the active films, showing 14.79 ± 0.25 and 3.50 ± 0.25 mM Trolox⋅ g extract in the film−1 for 0.75 GTE and 0.75 GSE films, respectively. It was also found that water barrier efficiency improved upon addition of the highest amount of GTE or GSE (1:0.75 alginate:extract ratio) which was ascribed to molecular interactions between the films' components, as demonstrated by infrared spectroscopy assays. M.J. Fabra is recipient of a Ramon y Cajal (RYC-2014-158) contract from the Spanish Ministry of Economy, Industry and Competitiveness. Authors would also like to thank the Central Support Service for Experimental Research (SCSIE) of the University of Valencia for the electron microscopy service. Peer reviewed 2018-03-21T11:52:43Z 2018-03-21T11:52:43Z 2018-02-23 artículo http://purl.org/coar/resource_type/c_6501 Food Hydrocolloids 81: 96-103 0268-005X http://hdl.handle.net/10261/162633 10.1016/j.foodhyd.2018.02.026 en Postprint https://doi.org/10.1016/j.foodhyd.2018.02.026 Sí open Elsevier
institution IATA ES
collection DSpace
country España
countrycode ES
component Bibliográfico
access En linea
databasecode dig-iata-es
tag biblioteca
region Europa del Sur
libraryname Biblioteca del IATA España
language English
topic Enteric viruses
Active packaging
Edible films
Grape seed extract (GSE)
Green tee extract (GTE)
Enteric viruses
Active packaging
Edible films
Grape seed extract (GSE)
Green tee extract (GTE)
spellingShingle Enteric viruses
Active packaging
Edible films
Grape seed extract (GSE)
Green tee extract (GTE)
Enteric viruses
Active packaging
Edible films
Grape seed extract (GSE)
Green tee extract (GTE)
Fabra, María José
Falcó, Irene
Randazzo, Walter
Sánchez Moragas, Gloria
López-Rubio, Amparo
Antiviral and antioxidant properties of active alginate edible films containing phenolic extracts
description In this work, novel active edible films having antiviral activity were developed through the solvent casting method. Emulsified edible films were prepared by adding lipids into alginate films in order to improve their water vapour permeability. In addition, two natural extracts rich in phenolic compounds, specifically a green tea extract (GTE) and a grape seed extract (GSE) were used as active agents. Interestingly, incorporating GTE or GSE within the biopolymer matrix, the films exhibited significant antiviral activity against murine norovirus (MNV) and hepatitis A virus (HAV) since ∼2 log reduction were recorded for the 0.75 g extract/g alginate in the film, being GTE more efficient than GSE. Furthermore, the incorporation of phenolic compounds imparted antioxidant capacity to the active films, showing 14.79 ± 0.25 and 3.50 ± 0.25 mM Trolox⋅ g extract in the film−1 for 0.75 GTE and 0.75 GSE films, respectively. It was also found that water barrier efficiency improved upon addition of the highest amount of GTE or GSE (1:0.75 alginate:extract ratio) which was ascribed to molecular interactions between the films' components, as demonstrated by infrared spectroscopy assays.
format artículo
topic_facet Enteric viruses
Active packaging
Edible films
Grape seed extract (GSE)
Green tee extract (GTE)
author Fabra, María José
Falcó, Irene
Randazzo, Walter
Sánchez Moragas, Gloria
López-Rubio, Amparo
author_facet Fabra, María José
Falcó, Irene
Randazzo, Walter
Sánchez Moragas, Gloria
López-Rubio, Amparo
author_sort Fabra, María José
title Antiviral and antioxidant properties of active alginate edible films containing phenolic extracts
title_short Antiviral and antioxidant properties of active alginate edible films containing phenolic extracts
title_full Antiviral and antioxidant properties of active alginate edible films containing phenolic extracts
title_fullStr Antiviral and antioxidant properties of active alginate edible films containing phenolic extracts
title_full_unstemmed Antiviral and antioxidant properties of active alginate edible films containing phenolic extracts
title_sort antiviral and antioxidant properties of active alginate edible films containing phenolic extracts
publisher Elsevier
publishDate 2018-02-23
url http://hdl.handle.net/10261/162633
work_keys_str_mv AT fabramariajose antiviralandantioxidantpropertiesofactivealginateediblefilmscontainingphenolicextracts
AT falcoirene antiviralandantioxidantpropertiesofactivealginateediblefilmscontainingphenolicextracts
AT randazzowalter antiviralandantioxidantpropertiesofactivealginateediblefilmscontainingphenolicextracts
AT sanchezmoragasgloria antiviralandantioxidantpropertiesofactivealginateediblefilmscontainingphenolicextracts
AT lopezrubioamparo antiviralandantioxidantpropertiesofactivealginateediblefilmscontainingphenolicextracts
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