Time Lags in Biological Models [electronic resource] /

In many biological models it is necessary to allow the rates of change of the variables to depend on the past history, rather than only the current values, of the variables. The models may require discrete lags, with the use of delay-differential equations, or distributed lags, with the use of integro-differential equations. In these lecture notes I discuss the reasons for including lags, especially distributed lags, in biological models. These reasons may be inherent in the system studied, or may be the result of simplifying assumptions made in the model used. I examine some of the techniques available for studying the solution of the equations. A large proportion of the material presented relates to a special method that can be applied to a particular class of distributed lags. This method uses an extended set of ordinary differential equations. I examine the local stability of equilibrium points, and the existence and frequency of periodic solutions. I discuss the qualitative effects of lags, and how these differ according to the choice of discrete or distributed lag. The models studied are drawn from the population dynamiCS of single species (logistic growth, the chemostat) and of interacting pairs of species (predation, mutualism), from cell population dynamiCS (haemopoiesis) and from biochemical kinetics (the Goodwin oscillator). The last chapter is devoted to a population model employing difference equations. All these models include non-linear terms.

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Main Authors: MacDonald, Norman. author., SpringerLink (Online service)
Format: Texto biblioteca
Language:eng
Published: Berlin, Heidelberg : Springer Berlin Heidelberg, 1978
Subjects:Mathematics., Mathematics, general.,
Online Access:http://dx.doi.org/10.1007/978-3-642-93107-9
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id KOHA-OAI-TEST:170367
record_format koha
institution COLPOS
collection Koha
country México
countrycode MX
component Bibliográfico
access En linea
En linea
databasecode cat-colpos
tag biblioteca
region America del Norte
libraryname Departamento de documentación y biblioteca de COLPOS
language eng
topic Mathematics.
Mathematics.
Mathematics, general.
Mathematics.
Mathematics.
Mathematics, general.
spellingShingle Mathematics.
Mathematics.
Mathematics, general.
Mathematics.
Mathematics.
Mathematics, general.
MacDonald, Norman. author.
SpringerLink (Online service)
Time Lags in Biological Models [electronic resource] /
description In many biological models it is necessary to allow the rates of change of the variables to depend on the past history, rather than only the current values, of the variables. The models may require discrete lags, with the use of delay-differential equations, or distributed lags, with the use of integro-differential equations. In these lecture notes I discuss the reasons for including lags, especially distributed lags, in biological models. These reasons may be inherent in the system studied, or may be the result of simplifying assumptions made in the model used. I examine some of the techniques available for studying the solution of the equations. A large proportion of the material presented relates to a special method that can be applied to a particular class of distributed lags. This method uses an extended set of ordinary differential equations. I examine the local stability of equilibrium points, and the existence and frequency of periodic solutions. I discuss the qualitative effects of lags, and how these differ according to the choice of discrete or distributed lag. The models studied are drawn from the population dynamiCS of single species (logistic growth, the chemostat) and of interacting pairs of species (predation, mutualism), from cell population dynamiCS (haemopoiesis) and from biochemical kinetics (the Goodwin oscillator). The last chapter is devoted to a population model employing difference equations. All these models include non-linear terms.
format Texto
topic_facet Mathematics.
Mathematics.
Mathematics, general.
author MacDonald, Norman. author.
SpringerLink (Online service)
author_facet MacDonald, Norman. author.
SpringerLink (Online service)
author_sort MacDonald, Norman. author.
title Time Lags in Biological Models [electronic resource] /
title_short Time Lags in Biological Models [electronic resource] /
title_full Time Lags in Biological Models [electronic resource] /
title_fullStr Time Lags in Biological Models [electronic resource] /
title_full_unstemmed Time Lags in Biological Models [electronic resource] /
title_sort time lags in biological models [electronic resource] /
publisher Berlin, Heidelberg : Springer Berlin Heidelberg,
publishDate 1978
url http://dx.doi.org/10.1007/978-3-642-93107-9
work_keys_str_mv AT macdonaldnormanauthor timelagsinbiologicalmodelselectronicresource
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spelling KOHA-OAI-TEST:1703672018-07-30T22:47:04ZTime Lags in Biological Models [electronic resource] / MacDonald, Norman. author. SpringerLink (Online service) textBerlin, Heidelberg : Springer Berlin Heidelberg,1978.engIn many biological models it is necessary to allow the rates of change of the variables to depend on the past history, rather than only the current values, of the variables. The models may require discrete lags, with the use of delay-differential equations, or distributed lags, with the use of integro-differential equations. In these lecture notes I discuss the reasons for including lags, especially distributed lags, in biological models. These reasons may be inherent in the system studied, or may be the result of simplifying assumptions made in the model used. I examine some of the techniques available for studying the solution of the equations. A large proportion of the material presented relates to a special method that can be applied to a particular class of distributed lags. This method uses an extended set of ordinary differential equations. I examine the local stability of equilibrium points, and the existence and frequency of periodic solutions. I discuss the qualitative effects of lags, and how these differ according to the choice of discrete or distributed lag. The models studied are drawn from the population dynamiCS of single species (logistic growth, the chemostat) and of interacting pairs of species (predation, mutualism), from cell population dynamiCS (haemopoiesis) and from biochemical kinetics (the Goodwin oscillator). The last chapter is devoted to a population model employing difference equations. All these models include non-linear terms.1. Introduction -- a. Discrete and Distributed Lag -- b. Origin of Lags in Biological Models -- c. Lag as an Alternative to Age Structure -- d. Lag as an Alternative to Spatial Structure -- e. The Effects of Lag -- f. Lags and Stochastic Models -- 2. Stability Analysis -- a. The Linear Chain Trick -- b. Instantaneous Models -- c. Models with a Single Discrete Lag -- d. Models with a Single Distributed Lag -- e. An Inequality for Distributed Lag -- f. The Monod Chemostat Model -- g. May’s Model of Obligate Mutualism -- 3. Periodic Solutions -- a. Periodic Solutions of the Linear Chain Equations -- b. The Method of Hastings, Tyson and Webster -- c. Hopf Bifurcation -- d. Numerical Integration -- 4. Logistic Growth of a Single Species -- a. Discrete Lag -- b. Distributed Lag in a Model of a Self-poisoning Population -- c. Linear Chain Calculations -- d. Hopf and H.T.W. Methods -- e. Constant Harvesting of a Population in the Presence of Lag -- f. Poincaré-Lindstedt Method for Discrete Lag -- g. An Epidemic Model Related to the Logistic Equation -- 5. Biochemical Oscillator Model -- a. The Goodwin Model -- b. Necessary Condition for Instability -- c. Expanding the Set of Equations -- d. A Single Goodwin Equation with Lag -- e. Discrete Lag in the Goodwin Equation -- 6. Models of Haemopoiesis -- a. Wheldon’s Model of Chronic Granulocytic Leukemia -- b. Two-lag Models of Cyclical Neutropenia -- c. Time Lag with Attrition; a Model of Cyclical Pancytopenia -- 7. Predation Models of the Volterra Type -- 8. Difference Equation Models -- a. Stability Analysis -- b. Conditions under which Spreading the Lag does not affect Local Stability -- c. Chaos in Discrete Dynamical Systems -- d. Extended Diapause in a Single Species Population Model -- e. Analogous Treatment of a Functional Differential Equation -- Supplementary Bibliography -- References.In many biological models it is necessary to allow the rates of change of the variables to depend on the past history, rather than only the current values, of the variables. The models may require discrete lags, with the use of delay-differential equations, or distributed lags, with the use of integro-differential equations. In these lecture notes I discuss the reasons for including lags, especially distributed lags, in biological models. These reasons may be inherent in the system studied, or may be the result of simplifying assumptions made in the model used. I examine some of the techniques available for studying the solution of the equations. A large proportion of the material presented relates to a special method that can be applied to a particular class of distributed lags. This method uses an extended set of ordinary differential equations. I examine the local stability of equilibrium points, and the existence and frequency of periodic solutions. I discuss the qualitative effects of lags, and how these differ according to the choice of discrete or distributed lag. The models studied are drawn from the population dynamiCS of single species (logistic growth, the chemostat) and of interacting pairs of species (predation, mutualism), from cell population dynamiCS (haemopoiesis) and from biochemical kinetics (the Goodwin oscillator). The last chapter is devoted to a population model employing difference equations. All these models include non-linear terms.Mathematics.Mathematics.Mathematics, general.Springer eBookshttp://dx.doi.org/10.1007/978-3-642-93107-9URN:ISBN:9783642931079